Inguma is a penetration testing toolkit entirely written in python. The framework includes modules to discover hosts, gather information about, fuzz targets, brute force user names and passwords and, of course, exploits. This program provides numerous tools for information gathering, target auditing and limited exploitation capabilities.
There are some good docs to get you up at their wiki site: Installation Guide, Getting Started, Console Quick Start, GUI Quick Start, Full Documentation. Follow them at Inguma Development.
Download it at http://code.google.com/p/inguma/